Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.52 |
| ▸ | ITGAV | P06756 | 7/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7338692 | 0.99 | ITGB3 (0.51) | ITGB3ITGA2BITGAVADRB2ADRB1 | |
| SCHEMBL7369685 | 0.90 | ITGB3 (0.47) | ITGB3ITGA2BITGAVKCNA5SLC1A2 | |
| Hydrochloric Acid SCHEMBL7370233 | 0.89 | ITGB3 (0.47) | ITGB3ITGA2BITGAVKCNA5SLC1A2 | |
| SCHEMBL7448188 | 0.86 | ITGB3 (0.46) | ITGB3ITGA2BITGAVADRB2ADRB1 | |
| SCHEMBL8617240 | 0.77 | ITGB3 (0.39) | ITGB3ITGA2BITGAVLMNASLC1A2 | |
| SCHEMBL7365261 | 0.77 | ITGB3 (0.47) | ITGB3ITGA2BITGAVKCNA5LMNA | |
| SCHEMBL7405338 | 0.76 | ACE (0.56) | ITGB3ITGA2BITGAVACE | |
| SCHEMBL7320593 | 0.76 | ACE (0.56) | ITGB3ITGA2BITGAVACE | |
| SCHEMBL8830082 | 0.74 | ITGB3 (0.63) | ITGB3ITGA2BITGAVLMNA | |
| SCHEMBL7345393 | 0.74 | ITGB3 (0.46) | ITGB3ITGA2BITGAVACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866705-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-03-03 | — | — | EP | claimed |
| EP-0866705-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-09-30 | — | — | EP | claimed |
| WO-1997014417-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-04-24 | — | — | WO | claimed |
| EP-0866705-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0866705-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997014417-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1997-04-24 | — | — | WO | disclosed |