Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.39 |
| ▸ | ITGAV | P06756 | 4/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619325 | 0.85 | MC4R (0.38) | ITGB3ITGA2BFKBP1AALDH1A1MEN1 | |
| SCHEMBL8618280 | 0.84 | ITGB3 (0.34) | ITGB3ITGA2BFKBP1AHSD17B10MEN1 | |
| SCHEMBL8621103 | 0.84 | ACE (0.34) | ITGB3ITGA2BITGAVFKBP1AALDH1A1 | |
| SCHEMBL8619314 | 0.83 | MTNR1A (0.40) | ITGB3ITGA2BALDH1A1MEN1KMT2A | |
| SCHEMBL7369685 | 0.80 | ITGB3 (0.47) | ITGB3ITGA2BITGAVSLC1A2SLC1A3 | |
| SCHEMBL7448188 | 0.80 | ITGB3 (0.46) | ITGB3ITGA2BITGAVSLC1A2SLC1A3 | |
| Hydrochloric Acid SCHEMBL7370233 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2BITGAVSLC1A2SLC1A3 | |
| SCHEMBL8619292 | 0.79 | GPBAR1 (0.34) | SLC1A2SLC1A3SLC1A1KCNH2FKBP1A | |
| SCHEMBL8617159 | 0.78 | DPP4 (0.37) | ITGB3ITGA2BALDH1A1OPRM1OPRD1 | |
| SCHEMBL7322436 | 0.77 | HRH3 (0.40) | ITGB3ITGA2BALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852045-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-22 | — | — | US | disclosed |