Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.37 |
| ▸ | IDH1 | O75874 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449699 | 0.81 | MLLT1 (0.38) | MLLT1TGFBR1DGAT2IDH1OPRM1 | |
| SCHEMBL7442673 | 0.76 | MLLT1 (0.34) | MLLT1TGFBR1DGAT2IDH1OPRM1 | |
| SCHEMBL7446445 | 0.75 | NPC1 (0.38) | MLLT1TGFBR1DGAT2IDH1LMNA | |
| SCHEMBL7454489 | 0.75 | NPC1 (0.38) | MLLT1TGFBR1DGAT2IDH1LMNA | |
| SCHEMBL7447505 | 0.75 | NPC1 (0.36) | MLLT1TGFBR1DGAT2IDH1LMNA | |
| SCHEMBL7447136 | 0.74 | ALDH1A1 (0.37) | MLLT1TGFBR1DGAT2IDH1LMNA | |
| SCHEMBL6455288 | 0.74 | MLLT1 (0.33) | MLLT1TGFBR1DGAT2 | |
| SCHEMBL7421109 | 0.74 | NPC1 (0.37) | MLLT1TGFBR1DGAT2IDH1LMNA | |
| SCHEMBL7445643 | 0.72 | NPC1 (0.35) | MLLT1TGFBR1DGAT2LMNAMAPT | |
| Hydrochloric Acid SCHEMBL7446984 | 0.71 | KLK1 (0.40) | LMNAMAPTNPC1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095025-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000001704-A2 | BENZIMIDAZOLES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-01-13 | — | — | WO | disclosed |