Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 0.67 |
| ▸ | MMP13 | P45452 | 10/20 | 0.67 |
| ▸ | MMP3 | P08254 | 9/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 6/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899829 | 0.93 | MMP2 (0.74) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7456050 | 0.92 | MMP2 (0.63) | MMP2MMP13MMP3TDP1MMP9 | |
| SCHEMBL7455165 | 0.88 | MMP13 (0.69) | MMP2MMP13MMP3TDP1MMP9 | |
| SCHEMBL7454899 | 0.87 | MMP2 (0.88) | MMP2MMP13MMP3TDP1MMP9 | |
| SCHEMBL7449471 | 0.84 | MMP2 (0.69) | MMP2MMP13MMP3MMP9 | |
| SCHEMBL7454871 | 0.81 | MMP2 (1.00) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7446562 | 0.80 | MMP13 (0.74) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7451546 | 0.77 | MMP2 (0.85) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7446824 | 0.76 | MMP13 (0.70) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL7555096 | 0.75 | MMP2 (0.66) | MMP2MMP13MMP3MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |