Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 12/20 | 0.69 |
| ▸ | MMP13 | P45452 | 10/20 | 0.69 |
| ▸ | MMP3 | P08254 | 9/20 | 0.69 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456050 | 0.93 | MMP2 (0.63) | MMP2MMP13MMP3MMP9EPHX2 | |
| SCHEMBL7899829 | 0.91 | MMP2 (0.74) | MMP2MMP13MMP3MMP9 | |
| SCHEMBL7448202 | 0.84 | MMP2 (0.67) | MMP2MMP13MMP3MMP9 | |
| SCHEMBL7446562 | 0.84 | MMP13 (0.74) | MMP2MMP13MMP3MMP9 | |
| SCHEMBL7454871 | 0.81 | MMP2 (1.00) | MMP2MMP13MMP3MMP9 | |
| SCHEMBL7455165 | 0.77 | MMP13 (0.69) | MMP2MMP13MMP3MMP9 | |
| SCHEMBL7454899 | 0.75 | MMP2 (0.88) | MMP2MMP13MMP3MMP9 | |
| SCHEMBL19074875 | 0.75 | L3MBTL1 (0.66) | EPHX2CXCR1CXCR2 | |
| SCHEMBL7450983 | 0.72 | MMP2 (1.00) | MMP2MMP13MMP3MMP9 | |
| SCHEMBL7451531 | 0.70 | MMP13 (0.80) | MMP2MMP13MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | claimed |
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |