Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.57 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.57 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 3/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448471 | 1.00 | ALDH1A1 (0.67) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL394112 | 0.88 | MEN1 (0.62) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL394111 | 0.88 | MEN1 (0.62) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL11619526 | 0.84 | ALDH1A1 (0.72) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL6989831 | 0.84 | ALDH1A1 (0.64) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL7426788 | 0.82 | ALDH1A1 (0.52) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL6988577 | 0.81 | ALDH1A1 (0.61) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL392680 | 0.81 | ALDH1A1 (1.00) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL4861809 | 0.81 | ALDH1A1 (1.00) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL478614 | 0.81 | ALDH1A1 (1.00) | ALDH1A1GAAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218382-B1 | FOR PROPHYLAXIS OR THERAPY OF THROMBOSIS | COR THERAPEUTICS, INC | 2001-04-17 | — | — | US | disclosed |
| EP-0994892-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999007732-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 1999-02-18 | — | — | WO | disclosed |