Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448536 | 1.00 | METAP2 (0.35) | METAP2CA12CA1CA2MMP2 | |
| SCHEMBL7443434 | 0.85 | — | — | |
| SCHEMBL7447134 | 0.80 | CA12 (0.34) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL7447154 | 0.80 | CA12 (0.34) | CA12CA1CA2MMP2CA9 | |
| SCHEMBL7445784 | 0.78 | — | — | |
| SCHEMBL7438232 | 0.78 | — | — | |
| SCHEMBL7442501 | 0.75 | MEN1 (0.41) | — | |
| SCHEMBL7444113 | 0.74 | PGD (0.32) | — | |
| SCHEMBL7448540 | 0.74 | CTSS (0.42) | METAP2CA12CA1CA2MMP2 | |
| SCHEMBL7440649 | 0.74 | TSHR (0.36) | MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |