Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELE | P16581 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | PROC | P04070 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7213522 | 1.00 | SELE (0.40) | SELEVCAM1F10F2PRSS1 | |
| SCHEMBL31140069 | 0.81 | BTK (0.47) | SELEVCAM1F10JAK3BTK | |
| SCHEMBL27504720 | 0.78 | SELE (0.39) | SELEVCAM1F10MEN1P2RY12 | |
| SCHEMBL7449196 | 0.77 | F2 (0.37) | F10F2PRSS1JAK3BTK | |
| SCHEMBL7219265 | 0.77 | F2 (0.37) | F10F2PRSS1JAK3BTK | |
| SCHEMBL7213537 | 0.76 | SELE (0.44) | SELEVCAM1F10F2JAK3 | |
| SCHEMBL7213538 | 0.75 | SELE (0.48) | SELEVCAM1F10MEN1KMT2A | |
| SCHEMBL27502979 | 0.75 | SELE (0.46) | SELEVCAM1F10MEN1P2RY12 | |
| SCHEMBL7540796 | 0.75 | F10 (0.45) | F10F2PRSS1PLGPLAT | |
| SCHEMBL7213552 | 0.75 | F10 (0.45) | F10F2PRSS1PLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001039759-A2 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-06-07 | — | — | WO | disclosed |