Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 17/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.48 |
| ▸ | ITGAV | P06756 | 7/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446810 | 0.97 | ITGB1 (0.51) | ITGB1ITGA5ITGAVITGA4MAPK1 | |
| SCHEMBL7447670 | 0.85 | ITGA4 (0.46) | ITGB1ITGA5ITGAVITGA4ALDH1A1 | |
| SCHEMBL7320647 | 0.84 | THRB (0.39) | MAPK1L3MBTL1 | |
| SCHEMBL7319356 | 0.84 | CA1 (0.37) | L3MBTL1 | |
| SCHEMBL7325907 | 0.82 | ITGB1 (0.69) | ITGB1ITGA5ITGAVITGA4MAPK1 | |
| SCHEMBL7321522 | 0.81 | ITGB1 (0.70) | ITGB1ITGA5ITGAVITGA4MAPK1 | |
| SCHEMBL6712429 | 0.76 | LMNA (0.40) | MAPK1ALDH1A1 | |
| SCHEMBL7322285 | 0.75 | MAPT (0.36) | MAPK1ALDH1A1 | |
| SCHEMBL5690666 | 0.74 | MAPT (0.37) | ALDH1A1 | |
| SCHEMBL5690742 | 0.74 | ITGB1 (0.71) | ITGB1ITGA5ITGAVITGA4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001972-A1 | SUBSTITUTED PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2000-05-24 | — | — | EP | claimed |
| WO-1999006431-A1 | SUBSTITUTED PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 1999-02-11 | — | — | WO | claimed |