Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447625 | 0.84 | TBXAS1 (0.63) | TBXAS1ALOX15FNTAFNTBPRMT5 | |
| SCHEMBL27279466 | 0.77 | ALOX15 (0.49) | TBXAS1ALOX15SIGMAR1HTR1DHTR1B | |
| SCHEMBL8776471 | 0.76 | HTR1A (0.56) | ALOX15HTR1AHTR7DRD4DRD2 | |
| SCHEMBL9866240 | 0.75 | ALOX15 (0.53) | TBXAS1ALOX15HTR1DHTR1BTERT | |
| SCHEMBL7100019 | 0.74 | ALOX15 (0.51) | TBXAS1ALOX15HTR1DHTR1BHRH1 | |
| Bicarbonate SCHEMBL28339489 | 0.73 | TBXAS1 (0.48) | TBXAS1ALOX15SIGMAR1TERTHRH3 | |
| SCHEMBL503743 | 0.72 | TBXAS1 (0.69) | TBXAS1ALOX15HTR1ATERT | |
| SCHEMBL28062565 | 0.72 | TBXAS1 (0.69) | TBXAS1ALOX15HTR1ATERT | |
| SCHEMBL11009198 | 0.72 | TBXAS1 (1.00) | TBXAS1TERT | |
| SCHEMBL1091991 | 0.72 | TBXAS1 (1.00) | TBXAS1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934293-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH TRYPTASE ACTIVITY | ARRIS PHARMACEUTICAL CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998004537-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING DISEASES ASSOCIATED WITH TRYPTASE ACTIVITY | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-02-05 | — | — | WO | disclosed |