Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 3/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450062 | 0.92 | L3MBTL1 (0.42) | ITGB3ITGA2BSTSYAP1CTSL | |
| SCHEMBL7450236 | 0.90 | ITGB3 (0.48) | ITGB3ITGA2BSTSYAP1USP30 | |
| SCHEMBL7443488 | 0.87 | ITGB3 (0.44) | ITGB3ITGA2BMAPTF2RKMT2A | |
| SCHEMBL7441387 | 0.86 | ITGB3 (0.61) | ITGB3ITGA2BF2R | |
| SCHEMBL7444745 | 0.86 | ITGB3 (0.61) | ITGB3ITGA2BF2R | |
| SCHEMBL7455696 | 0.85 | KMT2A (0.43) | ITGB3ITGA2BSTSYAP1USP30 | |
| SCHEMBL7440088 | 0.85 | ITGB3 (0.45) | ITGB3ITGA2BMAPTF2RKMT2A | |
| SCHEMBL7447910 | 0.85 | ITGB3 (0.61) | ITGB3ITGA2BF2R | |
| SCHEMBL7446367 | 0.83 | ITGB3 (0.48) | ITGB3ITGA2BSTSUSP30MAPK1 | |
| SCHEMBL7463085 | 0.83 | ITGB3 (0.44) | ITGB3ITGA2BSTSKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |