Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | UGT2B7 | P16662 | 4/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450778 | 0.73 | TSHR (0.35) | TSHRPPARD | |
| SCHEMBL7449448 | 0.69 | TSHR (0.41) | TSHRPPARD | |
| SCHEMBL21925055 | 0.69 | TSHR (0.50) | TSHRPPARDMMP1MMP2 | |
| SCHEMBL6635003 | 0.68 | CYP2D6 (0.31) | — | |
| SCHEMBL693202 | 0.68 | — | — | |
| SCHEMBL5022295 | 0.68 | FBP1 (0.36) | — | |
| SCHEMBL1547627 | 0.66 | — | — | |
| SCHEMBL11221727 | 0.66 | NOS3 (0.38) | — | |
| SCHEMBL1243991 | 0.66 | FDPS (0.44) | TSHRPPARDMMP1MMP2 | |
| SCHEMBL3490065 | 0.66 | LPAR3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087888-A1 | PYRAZOLOPYRIMIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | SK CHEMICALS CO., LTD. (KR) | 2001-11-22 | — | — | WO | disclosed |