Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.34 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441063 | 0.95 | KCNK3 (0.36) | KCNA5PDE4BALOX12KCNK3MMP12 | |
| SCHEMBL7437319 | 0.91 | ALDH1A1 (0.36) | ALOX12KCNK3LIMK2MMP12MMP13 | |
| SCHEMBL7437644 | 0.90 | EEF2K (0.41) | HSD17B2 | |
| SCHEMBL7442097 | 0.89 | ATM (0.37) | MEN1KMT2AHSP90AA1HSP90AB1HSD17B3 | |
| SCHEMBL7447436 | 0.87 | LIMK2 (0.37) | MEN1KMT2AKCNA5HSP90AA1HSP90AB1 | |
| SCHEMBL7445975 | 0.87 | POLB (0.38) | KMT2AKCNA5L3MBTL1ATM | |
| SCHEMBL7448174 | 0.86 | HSP90AA1 (0.38) | MEN1KMT2AHSP90AA1HSP90AB1PDE4B | |
| Ethane SCHEMBL7484090 | 0.84 | ALOX12 (0.38) | MEN1KMT2AHSP90AA1HSP90AB1HSD17B3 | |
| SCHEMBL7443310 | 0.84 | POLB (0.36) | ALOX12 | |
| SCHEMBL7405143 | 0.83 | HSD17B2 (0.39) | MEN1KMT2AHSP90AA1HSP90AB1HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994011361-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-05-26 | — | — | WO | claimed |
| WO-1994011361-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-05-26 | — | — | WO | disclosed |