Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 2/20 | 0.41 |
| ▸ | ATIC | P31939 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.36 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.36 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.35 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441063 | 0.93 | KCNK3 (0.36) | — | |
| SCHEMBL7450449 | 0.90 | MEN1 (0.37) | HSD17B2 | |
| SCHEMBL7450465 | 0.90 | ATIC (0.38) | EEF2KATICBRPF1SMARCA2PGAM1 | |
| SCHEMBL7437319 | 0.89 | ALDH1A1 (0.36) | PGAM1 | |
| SCHEMBL6174297 | 0.88 | PGAM1 (0.38) | EEF2KATICBRPF1SMARCA2PGAM1 | |
| Ethane SCHEMBL7482696 | 0.85 | ATIC (0.39) | EEF2KATICBRPF1SMARCA2PGAM1 | |
| SCHEMBL7445975 | 0.85 | POLB (0.38) | EEF2K | |
| SCHEMBL7448174 | 0.84 | HSP90AA1 (0.38) | HSD11B1 | |
| SCHEMBL7400129 | 0.84 | ATIC (0.40) | ATICBRPF1PGAM1HSD17B1HSD17B2 | |
| SCHEMBL7437641 | 0.83 | LMNA (0.38) | ATICBRPF1SMARCA2PGAM1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994011361-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-05-26 | — | — | WO | claimed |
| EP-1203770-A1 | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating hyperplasia and other diseases | PHARMACIA & UPJOHN COMPANY (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-1994011361-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-05-26 | — | — | WO | disclosed |