Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595395 | 0.89 | FDPS (0.39) | FDPSMAPK1LMNAHDAC1HDAC6 | |
| SCHEMBL7457885 | 0.88 | FDPS (0.37) | FDPSMAPK1LMNAHDAC1HDAC6 | |
| SCHEMBL7452466 | 0.87 | FDPS (0.38) | FDPSMAPK1LMNAHDAC1HDAC6 | |
| SCHEMBL7452578 | 0.85 | CPB2 (0.37) | FDPSMAPK1LMNAHDAC1HDAC6 | |
| SCHEMBL7452633 | 0.83 | FDPS (0.40) | FDPSMAPK1LMNAHDAC1HDAC6 | |
| SCHEMBL7459080 | 0.82 | FDPS (0.37) | FDPSMAPK1LMNAHDAC1HDAC6 | |
| SCHEMBL7453733 | 0.82 | FDPS (0.33) | FDPSMAPK1LMNAHDAC1HDAC6 | |
| SCHEMBL11904867 | 0.77 | FDPS (0.40) | FDPSLMNAHDAC1HDAC6TSHR | |
| SCHEMBL7451329 | 0.76 | FDPS (0.41) | FDPSLMNAHDAC1HDAC6TSHR | |
| SCHEMBL14125938 | 0.76 | FDPS (0.43) | FDPSMAPK1LMNAHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920430-A1 | PURINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998007725-A1 | PURINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-02-26 | — | — | WO | disclosed |