Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450504 | 0.83 | FDPS (0.41) | FDPSHDAC1HDAC6ALDH1A1KDM4E | |
| SCHEMBL7595395 | 0.82 | FDPS (0.39) | FDPSHDAC1HDAC6ALDH1A1KDM4E | |
| SCHEMBL7457457 | 0.82 | FDPS (0.42) | FDPSHDAC1HDAC6ALDH1A1CYP1A2 | |
| SCHEMBL7452466 | 0.78 | FDPS (0.38) | FDPSHDAC1HDAC6ALDH1A1KDM4E | |
| SCHEMBL7457885 | 0.77 | FDPS (0.37) | FDPSHDAC1HDAC6ALDH1A1KDM4E | |
| SCHEMBL7446851 | 0.77 | FDPS (0.40) | FDPSHDAC1HDAC6ALDH1A1CYP1A2 | |
| SCHEMBL7452578 | 0.76 | CPB2 (0.37) | FDPSHDAC1HDAC6ALDH1A1KDM4E | |
| SCHEMBL14125938 | 0.75 | FDPS (0.43) | FDPSHDAC1HDAC6ALDH1A1KDM4E | |
| SCHEMBL7459080 | 0.74 | FDPS (0.37) | FDPSHDAC1HDAC6ALDH1A1CYP1A2 | |
| SCHEMBL1831228 | 0.74 | USP5 (0.48) | FDPSHDAC1HDAC6ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920430-A1 | PURINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998007725-A1 | PURINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-02-26 | — | — | WO | disclosed |