Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 4/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454146 | 0.87 | DNMT3B (0.36) | FDPSHDAC1HDAC6IRAK4DNMT3B | |
| SCHEMBL7457885 | 0.82 | FDPS (0.37) | FDPSF10HDAC1HDAC6LMNA | |
| SCHEMBL7450504 | 0.82 | FDPS (0.41) | FDPSHDAC1HDAC6LMNAMAPK1 | |
| SCHEMBL7595395 | 0.77 | FDPS (0.39) | FDPSHDAC1HDAC6LMNAMAPK1 | |
| SCHEMBL11904867 | 0.75 | FDPS (0.40) | FDPSHDAC1HDAC6LMNAKDM4E | |
| SCHEMBL7452633 | 0.72 | FDPS (0.40) | FDPSHDAC1HDAC6LMNAMAPK1 | |
| SCHEMBL8464641 | 0.69 | LTA4H (0.35) | FDPSHDAC1HDAC6KDM4EALDH1A1 | |
| SCHEMBL8464663 | 0.69 | LTA4H (0.35) | FDPSHDAC1HDAC6KDM4EALDH1A1 | |
| SCHEMBL7451329 | 0.68 | FDPS (0.41) | FDPSHDAC1HDAC6LMNAALDH1A1 | |
| SCHEMBL14125938 | 0.66 | FDPS (0.43) | FDPSHDAC1HDAC6LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920430-A1 | PURINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998007725-A1 | PURINE DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-02-26 | — | — | WO | disclosed |