Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001469 | 0.84 | ALDH1A1 (0.60) | KDM4EALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL6352313 | 0.83 | SIRT2 (0.51) | KDM4ESMN1; SMN2ALDH1A1GAACYP1A2 | |
| SCHEMBL7449268 | 0.82 | MEN1 (0.68) | KDM4ESMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL7450408 | 0.81 | MEN1 (0.62) | KDM4ESMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL7457708 | 0.81 | MEN1 (0.56) | TSHRKDM4EHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL7452186 | 0.81 | APEX1 (0.53) | TSHRKDM4EHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL7454553 | 0.80 | MEN1 (0.79) | KDM4ESMN1; SMN2ALDH1A1HPGDRAB9A | |
| SCHEMBL7452179 | 0.80 | MEN1 (0.56) | TSHRKDM4EHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL7452610 | 0.80 | CASP3 (0.56) | KDM4ESMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL7453013 | 0.80 | KMT2A (0.55) | TSHRKDM4EHSD17B10SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098274-A2 | SULPHONAMIDE DERIVATIVES | CELLTECH CHIROSCIENCE LIMITED (GB) | 2001-12-27 | — | — | WO | disclosed |