Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954132 | 0.79 | MAOA (0.47) | ALDH1A1KMT2A | |
| SCHEMBL7451837 | 0.79 | MAOA (0.47) | ALDH1A1KMT2A | |
| SCHEMBL10509594 | 0.74 | ALDH1A1 (0.58) | ALDH1A1 | |
| SCHEMBL7451860 | 0.74 | ALDH1A1 (0.58) | ALDH1A1MEN1GAAKMT2ACHRM1 | |
| SCHEMBL7450900 | 0.71 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2APGR | |
| SCHEMBL7449747 | 0.71 | ALDH1A1 (0.59) | ALDH1A1CHRM1 | |
| SCHEMBL7455977 | 0.68 | EGFR (0.39) | ALDH1A1TDP1 | |
| SCHEMBL7448295 | 0.68 | ALDH1A1 (0.42) | ALDH1A1MEN1GAAKMT2ACHRM1 | |
| SCHEMBL7450349 | 0.67 | HTT (0.31) | ALDH1A1TDP1 | |
| SCHEMBL7450360 | 0.67 | HTT (0.31) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151361-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151361-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-12-08 | — | — | WO | disclosed |