Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.60 |
| ▸ | NPC1 | O15118 | 12/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672113 | 0.89 | RAB9A (0.72) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL5549552 | 0.83 | HDAC1 (0.70) | RAB9ANPC1MAPTHDAC1HDAC7 | |
| Trifluoroacetic Acid SCHEMBL7342343 | 0.80 | PLAU (0.60) | RAB9ANPC1MAPTHDAC1HDAC7 | |
| Trifluoroacetic Acid SCHEMBL7335035 | 0.79 | PLAU (0.63) | F2TMPRSS6 | |
| Anthracene SCHEMBL1558998 | 0.78 | CES1 (0.50) | HDAC1HDAC7HDAC8HDAC3HDAC4 | |
| Naphthalene SCHEMBL29443947 | 0.78 | CES1 (0.54) | MAPTHDAC6L3MBTL1CYP1A2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7335043 | 0.77 | F2 (0.38) | RAB9ANPC1MAPTHDAC1HDAC7 | |
| Trifluoroacetic Acid SCHEMBL7853602 | 0.77 | PLAU (0.70) | RAB9ANPC1KDM4ECASP3SENP7 | |
| SCHEMBL7450832 | 0.76 | RAB9A (0.51) | RAB9ANPC1MAPTHDAC1HDAC7 | |
| SCHEMBL9547503 | 0.76 | RAB9A (0.89) | RAB9ANPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000018-A2 | UROKINASE INHIBITORS | Abbott Laboratories (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999005096-A2 | UROKINASE INHIBITORS | ABBOTT LABORATORIES (US) | 1999-02-04 | — | — | WO | disclosed |