Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.72 |
| ▸ | NPC1 | O15118 | 13/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 7/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7450826 | 0.89 | RAB9A (0.60) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL9547503 | 0.85 | RAB9A (0.89) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL30697002 | 0.84 | MAPT (1.00) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL11049543 | 0.84 | MAPT (1.00) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL15727595 | 0.84 | RAB9A (0.68) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL3608965 | 0.83 | RAB9A (0.67) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL2229842 | 0.82 | NPC1 (0.76) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL516844 | 0.82 | RAB9A (0.65) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL8203018 | 0.82 | NPC1 (0.50) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL516845 | 0.82 | RAB9A (0.65) | RAB9ANPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11326018-B2 | Process for the synthesis of polyoxazolidinone compounds | COVESTRO DEUTSCHLAND AG (DE) | 2022-05-10 | — | — | US | claimed |
| US-11319398-B2 | Method for the production of polyoxazolidinone polymer compounds | COVESTRO DEUTSCHLAND AG (DE) | 2022-05-03 | — | — | US | claimed |
| EP-3577149-B1 | METHOD FOR THE PRODUCTION OF POLYOXAZOLIDINONE POLYMER COMPOUNDS | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2022-02-09 | — | — | EP | claimed |
| US-20210284785-A1 | PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS | COVESTRO DEUTSCHLAND AG (DE) | 2021-09-16 | — | — | US | claimed |
| EP-3500611-B1 | PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2021-08-11 | — | — | EP | claimed |
| CN-109642010-B | Synthesis method of polyoxazolidone compound | 科思创德国股份有限公司 | 2021-06-04 | — | — | CN | claimed |
| US-20210130527-A1 | METHOD FOR THE PRODUCTION OF POLYOXAZOLIDINONE POLYMER COMPOUNDS | COVESTRO DEUTSCHLAND AG (DE) | 2021-05-06 | — | — | US | claimed |
| US-10385167-B2 | Process for the synthesis of polyoxazolidinone compounds with high stability | COVESTRO DEUTSCHLAND AG (DE) | 2019-08-20 | — | — | US | claimed |
| EP-3500611-A1 | PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS | Covestro Deutschland AG (DE) | 2019-06-26 | — | — | EP | claimed |
| CN-109642010-A | The synthetic method of poly- Oxazolidinone compound | 科思创德国股份有限公司 | 2019-04-16 | — | — | CN | claimed |
| US-20180022871-A1 | PROCESS FOR THE SYNTHESIS OF POLYOXAZOLIDINONE COMPOUNDS WITH HIGH STABILITY | COVESTRO DEUTSCHLAND AG (DE) | 2018-01-25 | — | — | US | claimed |
| EP-1353926-B1 | MIKANOLIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USES | SOD CONSEILS RECH APPLIC (FR) | 2006-03-08 | — | — | EP | claimed |
| JP-2004533456-A | — | — | 2004-11-04 | — | — | JP | claimed |
| US-20040142999-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2004-07-22 | — | — | US | claimed |
| EP-1438039-A2 | PRODUCT COMPRISING MIKANOLIDE, DIHYDROMIKANOLIDE OR AN ANALOGUE THEREOF COMBINED WITH ANOTHER ANTI-CANCER AGENT FOR THERAPEUTIC USE IN CANCER TREATMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-07-21 | — | — | EP | claimed |
| EP-1397340-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-03-17 | — | — | EP | claimed |
| EP-1353926-A1 | MIKANOLIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USES | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 2003-10-22 | — | — | EP | claimed |
| WO-2002098850-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-12-12 | — | — | WO | claimed |
| WO-2002096348-A2 | PRODUCT COMPRISING MIKANOLIDE, DIHYDROMIKANOLIDE OR AN ANALOGUE THEREOF COMBINED WITH ANOTHER ANTI-CANCER AGENT FOR THERAPEUTIC USE IN CANCER TREATMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-12-05 | — | — | WO | claimed |
| WO-2002055523-A1 | MIKANOLIDE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-07-18 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142999-A1 | Novel compounds and compositions as cathepsin inhibitors | CTSS, CTSB, CTSE | RAB9A 512/4885NPC1 37/4885MAPT 2065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.