Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.51 |
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7342351 | 0.82 | PLAU (0.53) | RAB9ANPC1MAPTHDAC1HDAC7 | |
| SCHEMBL7335042 | 0.81 | PLAU (0.55) | — | |
| SCHEMBL28211672 | 0.80 | SMN1; SMN2 (0.47) | RAB9ANPC1MAPTHDAC1HDAC7 | |
| SCHEMBL5549552 | 0.79 | HDAC1 (0.70) | RAB9ANPC1MAPTHDAC1HDAC7 | |
| SCHEMBL2096821 | 0.77 | RAB9A (0.62) | RAB9ANPC1MAPTMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7450826 | 0.76 | RAB9A (0.60) | RAB9ANPC1MAPTHDAC1HDAC7 | |
| SCHEMBL2096819 | 0.76 | RAB9A (0.59) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL30216106 | 0.75 | KAT6A (0.60) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL3403454 | 0.75 | KAT6A (0.60) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL24969695 | 0.74 | ALDH1A1 (0.63) | RAB9ANPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000018-A2 | UROKINASE INHIBITORS | Abbott Laboratories (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999005096-A2 | UROKINASE INHIBITORS | ABBOTT LABORATORIES (US) | 1999-02-04 | — | — | WO | disclosed |