Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 8/20 | 0.52 |
| ▸ | CTSS | P25774 | 7/20 | 0.52 |
| ▸ | CTSB | P07858 | 7/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 5/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.50 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448513 | 1.00 | CTSL (0.53) | CTSLCTSKCTSSCTSBTACR1 | |
| SCHEMBL5257373 | 0.84 | CTSB (0.54) | CTSLCTSKCTSSCTSBTACR1 | |
| SCHEMBL7449390 | 0.78 | CTSK (0.56) | CTSLCTSKCTSSCTSBTACR1 | |
| SCHEMBL7444607 | 0.78 | CTSK (0.54) | CTSLCTSKCTSSCTSBTACR1 | |
| SCHEMBL11285648 | 0.77 | CHRM2 (0.48) | — | |
| SCHEMBL11285653 | 0.77 | CHRM2 (0.48) | — | |
| SCHEMBL7441597 | 0.76 | CTSK (0.54) | CTSLCTSKCTSSCTSBTACR1 | |
| SCHEMBL7441742 | 0.76 | CTSK (0.54) | CTSLCTSKCTSSCTSBTACR1 | |
| SCHEMBL7443686 | 0.76 | CTSK (0.54) | CTSLCTSKCTSSCTSBTACR1 | |
| SCHEMBL8089807 | 0.76 | CTSK (0.54) | CTSLCTSKCTSSCTSBTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817795-A1 | NOVEL 4-SUBSTITUTED-3-PEPTIDYL-AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE INHIBITOR | SYNPHAR LABORATORIES INC. (CA) | 1998-01-14 | — | — | EP | claimed |
| WO-1996032408-A1 | NOVEL 4-SUBSTITUTED-3-PEPTIDYL-AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE INHIBITOR | SYNPHAR LABORATORIES, INC. (US) | 1996-10-17 | — | — | WO | claimed |
| US-5986108-A | ENZYME INHIBITORS | SYNPHAR LABORATORIES, INC. (CA) | 1999-11-16 | — | — | US | disclosed |