Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.54 |
| ▸ | CTSS | P25774 | 8/20 | 0.54 |
| ▸ | CTSL | P07711 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 9/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441597 | 1.00 | CTSK (0.54) | CTSKCTSSCTSLALDH1A1ALOX15 | |
| SCHEMBL8085377 | 0.90 | CTSK (0.55) | CTSKCTSSCTSLCTSB | |
| SCHEMBL8086169 | 0.89 | GNPAT (0.44) | CTSKCTSSCTSLALDH1A1TACR1 | |
| SCHEMBL7436065 | 0.88 | CTSK (0.45) | CTSKCTSSCTSLCTSBELANE | |
| SCHEMBL7444607 | 0.88 | CTSK (0.54) | CTSKCTSSCTSLALDH1A1ALOX15 | |
| SCHEMBL8086238 | 0.87 | CTSK (0.55) | CTSKCTSSCTSLALDH1A1ALOX15 | |
| SCHEMBL7442716 | 0.86 | CTSK (0.55) | CTSKCTSSCTSLALDH1A1ALOX15 | |
| SCHEMBL7441709 | 0.85 | CTSL (0.56) | CTSKCTSSCTSLALDH1A1ALOX15 | |
| SCHEMBL7451264 | 0.84 | FAAH (0.43) | ALDH1A1 | |
| SCHEMBL7438536 | 0.82 | NOS2 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817795-B1 | NOVEL 4-SUBSTITUTED-3-PEPTIDYL-AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE INHIBITOR | NAEJA PHARMACEUTICAL INC (CA) | 2000-11-15 | — | — | EP | disclosed |