Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973001 | 0.74 | FDPS (0.33) | ANPEPERAP2LMNAGABRA1TSHR | |
| SCHEMBL9806690 | 0.69 | LMNA (0.38) | ANPEPERAP2LMNACYP3A4GABRA1 | |
| SCHEMBL7452509 | 0.68 | ANPEP (0.36) | ANPEPERAP2 | |
| SCHEMBL6945067 | 0.66 | LMNA (0.39) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL8369052 | 0.65 | LMNA (0.38) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL13930811 | 0.63 | MEN1 (0.32) | LMNAGABRA1GABRG2GABRB3GNAI3 | |
| SCHEMBL14212686 | 0.63 | KDM4E (0.39) | LMNAGABRA1GABRG2GABRB3GNAI3 | |
| SCHEMBL20798025 | 0.63 | ANPEP (0.47) | ANPEPERAP2GABRA1GABRA5 | |
| SCHEMBL7441473 | 0.63 | ARG1 (0.41) | LMNAGABRA1TSHRGABRG2GABRB3 | |
| SCHEMBL247607 | 0.62 | ARG1 (0.35) | LMNAGABRA1GABRG2GABRB3GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087888-A1 | PYRAZOLOPYRIMIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | SK CHEMICALS CO., LTD. (KR) | 2001-11-22 | — | — | WO | disclosed |