Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.35 |
| ▸ | ARG2 | P78540 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6150114 | 0.98 | ARG1 (0.34) | ARG1ARG2GABRA1GABRG2GABRB3 | |
| SCHEMBL13640032 | 0.77 | CYP1A2 (0.33) | — | |
| SCHEMBL5650003 | 0.77 | GBA1 (0.45) | GABRA1GABRG2GABRB3MEN1LMNA | |
| SCHEMBL1030996 | 0.75 | CYP1A2 (0.37) | MEN1LMNAKMT2A | |
| SCHEMBL13930811 | 0.73 | MEN1 (0.32) | GABRA1GABRG2GABRB3MEN1LMNA | |
| SCHEMBL14212686 | 0.73 | KDM4E (0.39) | GABRA1GABRG2GABRB3MEN1LMNA | |
| SCHEMBL1088624 | 0.72 | ALDH1A1 (0.46) | ARG1ARG2MEN1LMNACYP2D6 | |
| SCHEMBL6945067 | 0.71 | LMNA (0.39) | ARG1ARG2GABRA1GABRG2GABRB3 | |
| SCHEMBL89947 | 0.71 | — | — | |
| SCHEMBL3285306 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2842942-B1 | TRANS-2-DECENOIC ACID DERIVATIVE AND DRUG CONTAINING SAME | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2016-12-07 | — | — | EP | disclosed |
| US-9428477-B2 | Trans-2-decenoic acid derivative and drug containing same | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2016-08-30 | — | — | US | disclosed |
| EP-2188251-B1 | ARYLSULFONAMIDES WITH ANALGESIC ACTIVITY | BOEHRINGER INGELHEIM INT (DE) | 2015-04-29 | — | — | EP | disclosed |
| US-20150087823-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND DRUG CONTAINING SAME | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2015-03-26 | — | — | US | disclosed |
| EP-2842942-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND DRUG CONTAINING SAME | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2015-03-04 | — | — | EP | disclosed |
| EP-2061779-B1 | ARYL SULFONAMIDES WITH AN ANALGESIC ACTION | BOEHRINGER INGELHEIM INT (DE) | 2013-11-06 | — | — | EP | disclosed |
| US-8450306-B2 | Bradykinin B1-receptor antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-05-28 | — | — | US | disclosed |
| EP-2402329-B1 | Analgetic phenylsulphonamides | BOEHRINGER INGELHEIM INT (DE) | 2013-05-22 | — | — | EP | disclosed |
| US-8252785-B2 | Aryl sulfonamides as bradykinin-B1-receptor antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-08-28 | — | — | US | disclosed |
| EP-2402329-A1 | Analgetic phenylsulphonamides | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |
| EP-2284166-A1 | Arylsulfonamides with analgetic activity | Boehringer Ingelheim International GmbH (DE) | 2011-02-16 | — | — | EP | disclosed |
| US-20110021488-A1 | New Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-01-27 | — | — | US | disclosed |
| US-7858618-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-28 | — | — | US | disclosed |
| EP-2188251-A1 | ARYLSULFONAMIDES WITH ANALGESIC ACTIVITY | Boehringer Ingelheim International GmbH (DE) | 2010-05-26 | — | — | EP | disclosed |
| US-20090137545-A1 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-05-28 | — | — | US | disclosed |
| EP-2061779-A1 | ARYL SULFONAMIDES WITH AN ANALGESIC ACTION | Boehringer Ingelheim International GmbH (DE) | 2009-05-27 | — | — | EP | disclosed |
| WO-2009021758-A1 | ARYLSULFONAMIDES HAVING AN ANALGESIC EFFECT | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-19 | — | — | WO | disclosed |
| WO-2009021946-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-19 | — | — | WO | disclosed |
| EP-2025675-A1 | Arylsulfonamides with analgetic activity | Boehringer Ingelheim International GmbH (DE) | 2009-02-18 | — | — | EP | disclosed |
| WO-2008022945-A1 | ARYL SULFONAMIDES WITH AN ANALGESIC ACTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137545-A1 | Compounds | ADORA2B, ABCB11, CYP11B1 | ARG1 250/4885ARG2 468/4885GABRA1 261/4885 |
| US-20110021488-A1 | New Compounds | ABCG2, ADORA2B, ADORA3 | ARG1 288/4885ARG2 491/4885GABRA1 155/4885 |
| US-20150087823-A1 | TRANS-2-DECENOIC ACID DERIVATIVE AND DRUG CONTAINING SAME | GAP43, BDNF, PARK7 | ARG1 2381/4885ARG2 1129/4885GABRA1 910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.