Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 4/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4587581 | 0.90 | HTR7 (0.51) | PPARGPPARAHTR7PARP1MMP2 | |
| SCHEMBL4587605 | 0.89 | PPARG (0.48) | PPARGPPARAHTR7PARP1MMP2 | |
| Paliroden SCHEMBL4587135 | 0.87 | HTR7 (0.53) | PPARGPPARAHTR7PARP1KCNA3 | |
| Paliroden SCHEMBL29375649 | 0.87 | HTR7 (0.53) | PPARGPPARAHTR7PARP1KCNA3 | |
| SCHEMBL9501239 | 0.87 | SIGMAR1 (0.55) | PPARGPPARAHTR7PARP1KCNA3 | |
| SCHEMBL4589578 | 0.87 | PPARG (0.50) | PPARGPPARAHTR7PARP1KCNA3 | |
| SCHEMBL4588554 | 0.86 | HTR7 (0.52) | PPARGPPARAHTR7PARP1KCNA3 | |
| Hydrochloric Acid SCHEMBL9485989 | 0.86 | SIGMAR1 (0.54) | PPARGPPARAHTR7PARP1KCNA3 | |
| SCHEMBL4589037 | 0.85 | HTR7 (0.52) | PPARGPPARAHTR7PARP1KCNA3 | |
| SCHEMBL3453988 | 0.85 | HTR7 (0.50) | PPARGPPARAHTR7PARP1KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837848-B1 | 4-ARYL-1-PHENYLALKYL-1,2,3,6-TETRAHYDROPYRIDINES HAVING NEUROTROPHIC AND NEUROPROTECTIVE ACTIVITY | SANOFI SYNTHELABO (FR) | 2002-09-11 | — | — | EP | disclosed |