Paliroden

Paliroden

SCHEMBL29375649

FC(F)(F)c1cccc(C2=CCN(CCc3ccc(-c4ccccc4)cc3)CC2)c1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 2/20 0.53
PPARG P37231 1/20 0.53
PPARA Q07869 1/20 0.53
SIGMAR1 Q99720 4/20 0.50
PARP1 P09874 2/20 0.49
KCNA3 P22001 1/20 0.49
MAOB P27338 1/20 0.47
DRD2 P14416 1/20 0.46
DRD4 P21917 1/20 0.46
DRD3 P35462 1/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
TSHR P16473 1/20 0.45
NFKB1 P19838 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Paliroden SCHEMBL4587135 1.00 HTR7 (0.53) HTR7PPARGPPARASIGMAR1PARP1
SCHEMBL4587500 0.97 HTR7 (0.52) HTR7PPARGPPARASIGMAR1PARP1
Hydrochloric Acid SCHEMBL7393191 0.95 MAOB (0.53) HTR7PPARGPPARASIGMAR1PARP1
SCHEMBL9501239 0.95 SIGMAR1 (0.55) HTR7PPARGPPARASIGMAR1PARP1
Hydrochloric Acid SCHEMBL9485989 0.94 SIGMAR1 (0.54) HTR7PPARGPPARASIGMAR1PARP1
SCHEMBL4589037 0.93 HTR7 (0.52) HTR7PPARGPPARASIGMAR1PARP1
SCHEMBL4587555 0.93 HTR7 (0.54) HTR7PPARGPPARASIGMAR1PARP1
Hydrochloric Acid SCHEMBL7385918 0.92 HTR7 (0.53) HTR7PPARGPPARASIGMAR1PARP1
SCHEMBL4589363 0.92 PPARG (0.51) HTR7PPARGPPARASIGMAR1PARP1
SCHEMBL4589848 0.92 SIGMAR1 (0.55) HTR7PPARGPPARASIGMAR1PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
WO-2024191125-A1 METHOD FOR ACTIVATING ENDOGENOUS NEURAL STEM CELLS THROUGH LOW-INTENSITY FOCUSED ULTRASOUND TREATMENT 연세대학교 산학협력단 2024-09-19 WO claimed
US-20250344963-A1 METHODS FOR ACQUIRING AND ANALYZING NEUROMELANIN-SENSITIVE MRI UNIV OF OTTAWA INSTITUTE OF MENTAL HEALTH RESEARCH (CA) 2025-11-13 US disclosed
US-20250195477-A1 DEUTERATED IDAZOXAN AND METHODS OF USE THEREOF TERRAN BIOSCIENCES INC. 2025-06-19 US disclosed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO disclosed
EP-4545066-A2 4-PHENYL-TETRAHYDROPYRIDINE DERIVATIVES FOR TREATING HEARING DISEASES Cilcare Dev (FR) 2025-04-30 EP disclosed
EP-4479365-A1 DEUTERATED IDAZOXAN AND METHODS OF USE THEREOF Terran Biosciences Inc. (US) 2024-12-25 EP disclosed
CN-119053573-A Deuterated imidazole kesheng and methods of use thereof 人类生物科学股份有限公司 2024-11-29 CN disclosed
WO-2024211430-A2 METHODS AND COMPOSITIONS FOR TREATING NEURODEGENERATIVE CONDITIONS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-10-10 WO disclosed
CN-115645389-B Application of compound ML1 and derivative thereof in improving activity and function of cerebral cortex 刘晓栋 2024-10-01 CN disclosed
CN-118715014-A 4-Phenyl-tetrahydropyridine derivatives for the treatment of hearing disorders 西尔卡雷德夫公司 2024-09-27 CN disclosed
CN-115087665-A Engineered platelets for targeted delivery of therapeutic agents JPV01有限公司 2022-09-20 CN disclosed
EP-3368040-B1 METHODS AND COMPOSITIONS FOR RECOVERY FROM STROKE EIP PHARMA LLC (US) 2022-08-17 EP disclosed
US-20220251165-A1 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 LTD. (GB) 2022-08-11 US disclosed
EP-4026898-A1 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 Ltd (GB) 2022-07-13 EP disclosed
US-20220168243-A1 CORONAVIRUS TREATMENT COMPOSITIONS AND METHODS UNIV NEW YORK STATE RES FOUND (US) 2022-06-02 US disclosed
US-11291670-B2 Therapeutic approaches for treating Alzheimer disease and related disorders through a modulation of angiogenesis PHARNEXT (FR) 2022-04-05 US disclosed
US-20220041684-A1 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 LTD. (GB) 2022-02-10 US disclosed
EP-3947434-A2 ENGINEERED PLATELETS FOR TARGETED DELIVERY OF A THERAPEUTIC AGENT JPV01 Ltd (GB) 2022-02-09 EP disclosed
CN-114010641-A Methods for treating neurological disorders 爱普制药有限责任公司 2022-02-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220168243-A1 CORONAVIRUS TREATMENT COMPOSITIONS AND METHODS ACE, SARS1, ACE2 HTR7 3915/4885PPARG 3153/4885PPARA 2762/4885
US-20250195477-A1 DEUTERATED IDAZOXAN AND METHODS OF USE THEREOF XDH, INA, SLC6A3 HTR7 38/4885PPARG 565/4885PPARA 572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.