Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.61 |
| ▸ | BRD4 | O60885 | 8/20 | 0.59 |
| ▸ | BRD2 | P25440 | 2/20 | 0.59 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.59 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22105714 | 0.86 | PDE4A (0.55) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL516463 | 0.86 | PDE4A (0.81) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL22105715 | 0.85 | PDE4A (0.57) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL7465479 | 0.85 | BRD4 (0.76) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL7464093 | 0.85 | MAPK1 (0.57) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL7464482 | 0.82 | PDE4A (0.86) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL9565477 | 0.80 | PDE4A (0.65) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL7031729 | 0.80 | MEN1 (0.87) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL6661580 | 0.79 | BRD4 (0.51) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL9055277 | 0.78 | PDE4A (0.61) | PDE4AADORA2APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771813-B1 | Alkylxanthine phosphonates and alkylxanthine phosphine oxydes and their use as medicines | HOECHST AG (DE) | 2002-01-16 | — | — | EP | disclosed |
| US-5728686-A | TREATMENT OF MUSCULAR DYSTROPHY | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-17 | — | — | US | disclosed |
| CN-1158855-A | Alkylxanthine phosphonates and alkylxanthine phosphine oxides and their use as pharmacueticals | HOECHST AG (DE) | 1997-09-10 | — | — | CN | disclosed |
| EP-0771813-A1 | Alkylxanthine phosphonates and alkylxanthine phosphine oxydes and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-07 | — | — | EP | disclosed |