Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7454527 | 1.00 | CHIT1 (0.35) | CHIT1ALDH1A1MAPTCTSLGAA | |
| Trifluoroacetic Acid SCHEMBL7455827 | 0.94 | CTSL (0.34) | CHIT1ALDH1A1CTSLPLCG1 | |
| Trifluoroacetic Acid SCHEMBL7455819 | 0.94 | CTSL (0.34) | CHIT1ALDH1A1CTSLPLCG1 | |
| Trifluoroacetic Acid SCHEMBL7462415 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MAPTCTSLGAATGM2 | |
| Trifluoroacetic Acid SCHEMBL7462437 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MAPTCTSLGAATGM2 | |
| SCHEMBL7457350 | 0.84 | DPP8 (0.37) | ALDH1A1MAPTCTSLTGM2PLCG1 | |
| SCHEMBL7457355 | 0.84 | DPP8 (0.37) | ALDH1A1MAPTCTSLTGM2PLCG1 | |
| Trifluoroacetic Acid SCHEMBL7463897 | 0.83 | MEN1 (0.40) | CHIT1ALDH1A1MAPTCTSLTGM2 | |
| Trifluoroacetic Acid SCHEMBL7463901 | 0.83 | MEN1 (0.40) | CHIT1ALDH1A1MAPTCTSLTGM2 | |
| Trifluoroacetic Acid SCHEMBL7456788 | 0.82 | TGM2 (0.39) | ALDH1A1TGM2PLCG1KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882728-B1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO CO (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |