Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.42 |
| ▸ | LAP3 | P28838 | 3/20 | 0.40 |
| ▸ | FPR2 | P25090 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.38 |
| ▸ | GRN | P28799 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454824 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL12824095 | 0.81 | TAS1R3 (0.48) | FOLH1 | |
| SCHEMBL614517 | 0.80 | ALDH1A1 (0.36) | ALDH1A1KMT2AMAPTFOLH1 | |
| SCHEMBL7038338 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL7038343 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL2286681 | 0.78 | TGFBR1 (0.42) | ALDH1A1KMT2AMAPTMME | |
| SCHEMBL2286678 | 0.78 | TGFBR1 (0.42) | ALDH1A1KMT2AMAPTMME | |
| SCHEMBL10679490 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPTFPR2MME | |
| SCHEMBL1706955 | 0.76 | TSHR (0.33) | ALDH1A1KMT2AMAPT | |
| SCHEMBL747873 | 0.76 | MAPT (0.45) | ALDH1A1KMT2AMAPTFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941104-A4 | PEPTIDE SYNTHESIS WITH SULFONYL PROTECTING GROUPS | UNIV CALIFORNIA (US) | 2002-01-02 | — | — | EP | disclosed |
| EP-0941104-A1 | PEPTIDE SYNTHESIS WITH SULFONYL PROTECTING GROUPS | The Regents of the University of California (US) | 1999-09-15 | — | — | EP | disclosed |
| US-5942601-A | SOLID PHASE PEPTIDE SYNTHESIS BY ATTACHING SULFONYL GROUP ALPHA AMINO PROTECTED AMINO ACID TO SECOND AMINO ACID STABLY ATTACHED TO POLYMER SUPPORT, SEPARATING SOLID POLYMER SUPPORT FROM MIXTURE, REMOVING SULFONYL GROUP, REPEATING SYNTHESIS | THE REAGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-08-24 | — | — | US | disclosed |
| WO-1998024461-A1 | PEPTIDE SYNTHESIS WITH SULFONYL PROTECTING GROUPS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-06-11 | — | — | WO | disclosed |