Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6360325 | 0.87 | MAPT (0.43) | FAAHMAPTL3MBTL1RAB9AKMT2A | |
| SCHEMBL7972739 | 0.77 | MAPT (0.43) | MAPTL3MBTL1RAB9AKMT2AMEN1 | |
| SCHEMBL8107555 | 0.75 | TMEM97 (0.43) | MAPTRAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL6687407 | 0.74 | TMEM97 (0.44) | MAPTRAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5158515 | 0.71 | TMEM97 (0.42) | MAPTALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7967548 | 0.69 | MAPT (0.41) | MAPTL3MBTL1RAB9AKMT2AMEN1 | |
| SCHEMBL6801243 | 0.68 | RAB9A (0.37) | L3MBTL1RAB9AALDH1A1KDM4EPOLB | |
| SCHEMBL28097254 | 0.68 | AKR1C3 (0.44) | FAAHMAPTL3MBTL1RAB9AKMT2A | |
| SCHEMBL9032769 | 0.66 | RAB9A (0.43) | MAPTL3MBTL1RAB9AKMT2AMEN1 | |
| SCHEMBL24310659 | 0.65 | HTR3A (0.49) | MAPTRAB9AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0890119-A4 | PHOTOCHROMIC NAPHTHOPYRAN COMPOSITIONS OF NEUTRAL COLOR | TRANSITIONS OPTICAL INC (US) | 2002-07-17 | — | — | EP | disclosed |
| EP-0890119-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOSITIONS OF NEUTRAL COLOR | TRANSITIONS OPTICAL, INC. (US) | 1999-01-13 | — | — | EP | disclosed |
| WO-1997037254-A1 | PHOTOCHROMIC NAPHTHOPYRAN COMPOSITIONS OF NEUTRAL COLOR | TRANSITIONS OPTICAL, INC. (US) | 1997-10-09 | — | — | WO | disclosed |