Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455169 | 0.80 | NPC1 (0.54) | NPC1MEN1KMT2ANQO1MAOA | |
| SCHEMBL9765553 | 0.79 | MEN1 (0.54) | NPC1MEN1KMT2ANQO1ALDH1A1 | |
| SCHEMBL6370043 | 0.78 | GPR84 (0.58) | NPC1MEN1KMT2ANQO1MAOA | |
| SCHEMBL19570740 | 0.78 | ALDH1A1 (0.42) | MAOAKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL20668950 | 0.76 | ALDH1A1 (0.41) | MEN1KMT2AMAOAKDM4EALDH1A1 | |
| SCHEMBL4094512 | 0.75 | MEN1 (0.47) | NPC1MEN1KMT2AMAOAKDM4E | |
| SCHEMBL14280975 | 0.75 | CA1 (0.55) | NPC1MEN1KMT2ANQO1KDM4E | |
| SCHEMBL7331674 | 0.74 | NPC1 (1.00) | NPC1MEN1KMT2AMAOAKDM4E | |
| Water SCHEMBL9036802 | 0.73 | MEN1 (0.46) | NPC1MEN1KMT2AMAOAKDM4E | |
| SCHEMBL21624244 | 0.73 | NPC1 (0.67) | NPC1MEN1KMT2AMAOAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163372-A4 | CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES | PRINCETON SEPARATIONS (US) | 2002-10-02 | — | — | EP | claimed |
| EP-1163372-A1 | CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES | Princeton Separations (US) | 2001-12-19 | — | — | EP | claimed |
| WO-2000056933-A1 | CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES | PRINCETON SEPARATIONS (US) | 2000-09-28 | — | — | WO | claimed |
| EP-1163372-A4 | CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES | PRINCETON SEPARATIONS (US) | 2002-10-02 | — | — | EP | disclosed |
| EP-1163372-A1 | CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES | Princeton Separations (US) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000056933-A1 | CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES | PRINCETON SEPARATIONS (US) | 2000-09-28 | — | — | WO | disclosed |