Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6370043 | 0.85 | GPR84 (0.58) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL9040694 | 0.85 | ALDH1A1 (0.60) | MAPTALDH1A1NPSR1RAD52SMN1; SMN2 | |
| SCHEMBL13100481 | 0.81 | ALDH1A1 (0.56) | MAPTALDH1A1RAD52NQO1TDP1 | |
| SCHEMBL5334950 | 0.80 | CYP1A2 (0.59) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL7455184 | 0.79 | NPC1 (0.59) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL9132527 | 0.79 | CYP1A2 (0.62) | NPC1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9765521 | 0.79 | MAPT (0.54) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL10634616 | 0.77 | ALDH1A1 (0.41) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL4181934 | 0.77 | ALDH1A1 (0.58) | MEN1KMT2AMAPTALDH1A1GPR84 | |
| SCHEMBL9765549 | 0.76 | MAOA (0.54) | MEN1KMT2ANPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272621-B1 | Method for the production of 5H-dibenzo[a,d]cyclohepten-5-ones | BASF Aktiengesellschaft (DE) | 1991-11-27 | — | — | EP | disclosed |
| US-4845302-A | Preparation of 5H-dibenzo[a,d]cyclohepten-5-ones | BASF AKTIENGSELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |
| EP-0272621-A2 | Method for the production of 5H-dibenzo[a,d]cyclohepten-5-ones | BASF Aktiengesellschaft (DE) | 1988-06-29 | — | — | EP | disclosed |