SCHEMBL14280975

SCHEMBL14280975

COc1cc2c3ccccc3c3cc(OC)c(OC)cc3c2cc1OC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.55
CA2 P00918 4/20 0.55
CA7 P43166 3/20 0.55
CA9 Q16790 3/20 0.55
CA12 O43570 2/20 0.55
CA14 Q9ULX7 2/20 0.55
CA4 P22748 1/20 0.55
NQO1 P15559 1/20 0.52
MEN1 O00255 1/20 0.52
NPC1 O15118 1/20 0.52
KMT2A Q03164 1/20 0.52
ALDH1A1 P00352 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
NQO2 P16083 1/20 0.50
KDM4E B2RXH2 1/20 0.50
MAPK1 P28482 1/20 0.50
IDO1 P14902 1/20 0.48
MAPT P10636 1/20 0.48
PDPK1 O15530 1/20 0.47
EP300 Q09472 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19999173 0.92 CA12 (0.52) CA1CA2CA7CA9CA12
SCHEMBL17445646 0.91 MAPT (0.50) CA1CA2CA7CA9CA12
SCHEMBL28966740 0.87 MEN1 (0.43) CA1CA2CA7CA9CA12
SCHEMBL29368836 0.85 CYP3A4 (0.53) CA1CA2CA7CA9CA12
SCHEMBL1711296 0.85 CYP3A4 (0.53) CA1CA2CA7CA9CA12
SCHEMBL26937808 0.84 EP300 (0.53) CA1CA2CA7CA9CA12
SCHEMBL11062870 0.80 EP300 (0.50) CA1CA2CA7CA9CA12
SCHEMBL11716407 0.80 EP300 (0.42) CA1CA2CA7CA9CA12
SCHEMBL13100481 0.79 ALDH1A1 (0.56) NQO1ALDH1A1NQO2KDM4EMAPK1
SCHEMBL12126778 0.77 ACACA (0.49) NQO1MEN1NPC1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2023-06-13 US disclosed
US-20210376247-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2021-12-02 US disclosed
US-11152574-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2021-10-19 US disclosed
US-11094888-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2021-08-17 US disclosed
US-20210083194-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2021-03-18 US disclosed
US-10283717-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2019-05-07 US disclosed
US-10263192-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2019-04-16 US disclosed
US-9960360-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 US disclosed
US-20180090685-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2018-03-29 US disclosed
US-20180040828-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2018-02-08 US disclosed
US-9403825-B2 Compound, solar cell module, and photovoltaic power generation device SHARP KABUSHIKI KAISHA (JP) 2016-08-02 US disclosed
US-9403825-B2 Compound, solar cell module, and photovoltaic power generation device SHARP KABUSHIKI KAISHA (JP) 2016-08-02 US disclosed
US-20160020403-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2016-01-21 US disclosed
US-20160002238-A1 COMPOUND, SOLAR CELL MODULE, AND PHOTOVOLTAIC POWER GENERATION DEVICE SHARP KABUSHIKI KAISHA (JP) 2016-01-07 US disclosed
US-20160002238-A1 COMPOUND, SOLAR CELL MODULE, AND PHOTOVOLTAIC POWER GENERATION DEVICE SHARP KABUSHIKI KAISHA (JP) 2016-01-07 US disclosed
US-20080014464-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2008-01-17 US disclosed
US-20080014464-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2008-01-17 US disclosed
WO-2007052838-A1 POLYMER FILM, METHOD FOR PRODUCING POLYMER FILM, OPTICAL FILM AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2007-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11152574-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle RPL21, RPS21, AOC2 CA1 4391/4885CA2 3670/4885CA7 4257/4885
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle RPS17, RPS19, CDK17 CA1 4770/4885CA2 4544/4885CA7 1987/4885
US-20210083194-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE RPL21, RPS21, AOC2 CA1 4391/4885CA2 3670/4885CA7 4257/4885
US-20160002238-A1 COMPOUND, SOLAR CELL MODULE, AND PHOTOVOLTAIC POWER GENERATION DEVICE CRY1, CCNE2, CCND2 CA1 3790/4885CA2 2365/4885CA7 3151/4885
US-20180090685-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE SLC18A1, SLC18A2, AOC2 CA1 4791/4885CA2 4678/4885CA7 4466/4885
US-10283717-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle SLC18A1, SLC18A2, AOC2 CA1 4791/4885CA2 4678/4885CA7 4466/4885
US-11094888-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle SLC18A1, SLC18A2, AOC2 CA1 4791/4885CA2 4678/4885CA7 4466/4885
US-10263192-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle SLC18A1, SLC18A2, AOC2 CA1 4791/4885CA2 4678/4885CA7 4466/4885
US-20180040828-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE SLC18A1, SLC18A2, AOC2 CA1 4791/4885CA2 4678/4885CA7 4466/4885
US-20160020403-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE SLC18A1, SLC18A2, AOC2 CA1 4791/4885CA2 4678/4885CA7 4466/4885
US-20210376247-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE RPS17, RPS19, CDK17 CA1 4770/4885CA2 4544/4885CA7 1987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.