Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459723 | 0.79 | KDM4E (0.56) | PTGS2KDM4ELMNAGAAALDH1A1 | |
| SCHEMBL7454603 | 0.79 | KDM4E (0.56) | PTGS2KDM4EMAPTLMNAGAA | |
| SCHEMBL5186788 | 0.79 | ALDH1A1 (0.74) | KDM4EMAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL15215659 | 0.78 | POLB (0.72) | KDM4EMAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL7459393 | 0.77 | MAPK8 (0.53) | PTGS2KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL11173864 | 0.77 | RAB9A (0.75) | KDM4EMAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL7454826 | 0.76 | PTGS2 (0.58) | PTGS2KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL7297544 | 0.76 | ALDH1A1 (0.52) | PTGS2KDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL8489624 | 0.75 | NAMPT (0.60) | PTGS2KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL10934987 | 0.74 | ALDH1A1 (0.50) | KDM4EMAPTSMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819118-B1 | POTASSIUM ION CHANNEL BLOCKERS | POLYCHIP PHARMACEUTICALS PTY (AU) | 2002-09-18 | — | — | EP | disclosed |
| US-5929082-A | SULFONYL(THIO)UREA AND SULFONYLGUANIDINE COMPOUNDS; TREATMENT OF DIABETES, CARDIAC ARRHYTHMIAS, ISCHEMIA, HYPOXIC CARDIOVASCUALR DISORDERS AND CANCER | POLYCHIP PHARMACEUTICALS PTY LTD (AU) | 1999-07-27 | — | — | US | disclosed |
| EP-0819118-A4 | POTASSIUM ION CHANNEL BLOCKERS | POLYCHIP PHARMACEUTICALS PTY (AU) | 1998-04-29 | — | — | EP | disclosed |
| EP-0819118-A1 | POTASSIUM ION CHANNEL BLOCKERS | Polychip Pharmaceuticals Pty. Ltd. (AU) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996030341-A1 | POTASSIUM ION CHANNEL BLOCKERS | POLYCHIP PHARMACEUTICALS PTY. LTD. (AU) | 1996-10-03 | — | — | WO | disclosed |