Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2499200 | 0.89 | MAPT (0.60) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6280285 | 0.83 | MAPT (0.54) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5685561 | 0.81 | ALDH1A1 (0.56) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6281258 | 0.81 | MAPT (0.56) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7455153 | 0.81 | SMPD1 (0.57) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8597038 | 0.81 | TSHR (0.56) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28500412 | 0.77 | MAPT (0.67) | RAB9AMAPTALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL2395083 | 0.75 | ALDH1A1 (0.65) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7455676 | 0.74 | NPC1 (0.50) | RAB9AALDH1A1LMNASMN1; SMN2HSD11B1 | |
| SCHEMBL11599893 | 0.74 | ALDH1A1 (0.59) | RAB9AMAPTALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002042261-A2 | PROCESS FOR PREPARING α-(3-ARYLTHIO)-ACETOPHENONES | ELI LILLY AND COMPANY (US) | 2002-05-30 | — | — | WO | disclosed |
| WO-1999025707-A1 | 2-ARYLBENZO[b]THIOPHENES USEFUL FOR THE TREATMENT OF ESTROGEN DEPRIVATION SYNDROME | ELI LILLY AND COMPANY (US) | 1999-05-27 | — | — | WO | disclosed |