Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2499200 | 0.88 | MAPT (0.60) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL8597038 | 0.82 | TSHR (0.56) | RAB9ASMN1; SMN2NPC1HPGDALDH1A1 | |
| SCHEMBL6280285 | 0.82 | MAPT (0.54) | RAB9ASMN1; SMN2NPC1HPGDALDH1A1 | |
| SCHEMBL7455682 | 0.81 | RAB9A (0.51) | RAB9ASMN1; SMN2NPC1HPGDALDH1A1 | |
| SCHEMBL6281258 | 0.80 | MAPT (0.56) | RAB9ASMN1; SMN2NPC1HPGDALDH1A1 | |
| SCHEMBL5685561 | 0.80 | ALDH1A1 (0.56) | RAB9ASMN1; SMN2NPC1HPGDALDH1A1 | |
| SCHEMBL7455151 | 0.77 | MAOB (0.53) | SMPD1HDAC1HDAC8HDAC6RAB9A | |
| SCHEMBL29375753 | 0.77 | SMPD1 (0.75) | SMPD1HDAC1HDAC8HDAC6RAB9A | |
| SCHEMBL1029034 | 0.77 | SMPD1 (0.75) | SMPD1HDAC1HDAC8HDAC6RAB9A | |
| SCHEMBL8843713 | 0.76 | SMN1; SMN2 (0.90) | SMPD1HDAC1HDAC8HDAC6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002042261-A2 | PROCESS FOR PREPARING α-(3-ARYLTHIO)-ACETOPHENONES | ELI LILLY AND COMPANY (US) | 2002-05-30 | — | — | WO | disclosed |