Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450055 | 0.93 | ITGB3 (0.42) | KMT2AITGB3ITGA2BGPR119STS | |
| SCHEMBL7450244 | 0.90 | KMT2A (0.45) | KMT2AITGB3ITGA2BGPR119STS | |
| SCHEMBL7443492 | 0.87 | KMT2A (0.41) | KMT2AITGB3ITGA2BKDM4EPKM | |
| SCHEMBL7441383 | 0.86 | ITGB3 (0.51) | KMT2AITGB3ITGA2BGAANPC1 | |
| SCHEMBL7444755 | 0.86 | ITGB3 (0.56) | KMT2AITGB3ITGA2BGPR119STS | |
| SCHEMBL7445255 | 0.85 | GPR119 (0.44) | KMT2AITGB3ITGA2BGPR119STS | |
| SCHEMBL7455702 | 0.85 | ITGB3 (0.46) | KMT2AITGB3ITGA2BGPR119STS | |
| SCHEMBL7440080 | 0.85 | KMT2A (0.42) | KMT2AITGB3ITGA2BKDM4EPKM | |
| SCHEMBL7447915 | 0.85 | ITGB3 (0.44) | KMT2AITGB3ITGA2BGPR119STS | |
| SCHEMBL7463087 | 0.83 | RAB9A (0.44) | KMT2ASTSKDM4EGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |