Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 8/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456405 | 0.93 | TDP1 (0.37) | SIGMAR1ALDH1A1DPP8DPP9CCR5 | |
| SCHEMBL7457694 | 0.91 | SIGMAR1 (0.38) | SIGMAR1ALDH1A1LMNADPP8DPP9 | |
| SCHEMBL7456168 | 0.89 | SIGMAR1 (0.39) | SIGMAR1ALDH1A1DPP8DPP9CCR5 | |
| SCHEMBL8102813 | 0.86 | SIGMAR1 (0.33) | SIGMAR1ALDH1A1LMNADPP8DPP9 | |
| SCHEMBL7453536 | 0.86 | SIGMAR1 (0.33) | SIGMAR1ALDH1A1LMNADPP8DPP9 | |
| SCHEMBL7457935 | 0.85 | CCR2 (0.37) | SIGMAR1ALDH1A1LMNADPP8DPP9 | |
| SCHEMBL7449048 | 0.84 | CCR5 (0.37) | SIGMAR1ALDH1A1LMNADPP8DPP9 | |
| SCHEMBL7454118 | 0.84 | CCR5 (0.37) | SIGMAR1ALDH1A1LMNADPP8DPP9 | |
| SCHEMBL5670553 | 0.84 | CCR5 (0.32) | SIGMAR1ALDH1A1LMNADPP8DPP9 | |
| SCHEMBL7456316 | 0.84 | POLB (0.37) | SIGMAR1ALDH1A1DPP8DPP9CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882728-B1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO CO (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |