Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456013 | 0.93 | SIGMAR1 (0.40) | TDP1SIGMAR1DPP8DPP9ATM | |
| SCHEMBL7456316 | 0.90 | POLB (0.37) | TDP1SIGMAR1DPP8DPP9ATM | |
| SCHEMBL7454106 | 0.89 | DPP8 (0.35) | TDP1SIGMAR1DPP8DPP9ATM | |
| SCHEMBL7457360 | 0.88 | PLCG1 (0.37) | TDP1SIGMAR1DPP8DPP9ATM | |
| SCHEMBL7462425 | 0.85 | ALDH1A1 (0.33) | TDP1SIGMAR1DPP8DPP9ATM | |
| SCHEMBL7453403 | 0.85 | CCR5 (0.32) | TDP1DPP8DPP9CCR5RAB9A | |
| SCHEMBL7457694 | 0.84 | SIGMAR1 (0.38) | SIGMAR1DPP8DPP9CCR5ALDH1A1 | |
| SCHEMBL7460549 | 0.83 | DPP8 (0.37) | TDP1DPP8DPP9ATMCCR5 | |
| SCHEMBL7460727 | 0.83 | DPP8 (0.37) | TDP1DPP8DPP9ATMCCR5 | |
| SCHEMBL7456168 | 0.82 | SIGMAR1 (0.39) | TDP1SIGMAR1DPP8DPP9PLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882728-B1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO CO (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |