Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 16/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL7221833 | 0.97 | ADORA3 (0.55) | ADORA3ADORA1ADORA2AADORA2BHTR2C | |
| SCHEMBL7230980 | 0.93 | ADORA3 (0.69) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL7456399 | 0.92 | PGK1 (0.53) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL7221838 | 0.91 | ADORA3 (0.48) | ADORA3ADORA1ADORA2AADORA2BHTR2C | |
| SCHEMBL7522964 | 0.91 | ADORA3 (0.48) | ADORA3ADORA1ADORA2AADORA2BHTR2C | |
| SCHEMBL7221837 | 0.91 | ADORA3 (0.48) | ADORA3ADORA1ADORA2AADORA2BHTR2C | |
| Formic Acid SCHEMBL7224962 | 0.89 | PGK1 (0.50) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL7454558 | 0.89 | PGK1 (0.60) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL5138486 | 0.87 | ADORA3 (0.59) | ADORA3ADORA1ADORA2AADORA2BHTR2C | |
| SCHEMBL5138159 | 0.86 | ADORA3 (0.58) | ADORA3ADORA1ADORA2AADORA2BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948509-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-10-16 | — | — | EP | claimed |
| US-6426337-B1 | ANTIINFLAMMATORY AGENTS | SMITHKLINE BEECHAM CORPORATION | 2002-07-30 | — | — | US | claimed |