Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 9/20 | 0.56 |
| ▸ | KDR | P35968 | 8/20 | 0.56 |
| ▸ | MET | P08581 | 5/20 | 0.52 |
| ▸ | AXL | P30530 | 5/20 | 0.52 |
| ▸ | MERTK | Q12866 | 3/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.49 |
| ▸ | KIT | P10721 | 2/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | LYN | P07948 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456971 | 0.88 | NR4A2 (0.51) | PDGFRAKDRMETAXLMERTK | |
| SCHEMBL7461154 | 0.88 | PDGFRA (0.49) | PDGFRAKDRMETAXLMERTK | |
| Hydrochloric Acid SCHEMBL27295456 | 0.86 | NR4A2 (0.50) | PDGFRAKDRMETAXLMERTK | |
| SCHEMBL22407497 | 0.84 | PDGFRA (0.55) | PDGFRAKDRMETAXLMERTK | |
| SCHEMBL27303568 | 0.83 | KDR (0.49) | PDGFRAKDRMETAXLMERTK | |
| SCHEMBL20782867 | 0.82 | PDGFRA (0.53) | PDGFRAKDRMETAXLMERTK | |
| SCHEMBL9858440 | 0.81 | LMNA (0.52) | PDGFRAKDRMETAXLMERTK | |
| SCHEMBL7482722 | 0.79 | MET (0.54) | PDGFRAKDRMETAXLMERTK | |
| SCHEMBL9858637 | 0.78 | CCNC (0.63) | PDGFRAKDRMETAXLMERTK | |
| SCHEMBL7467913 | 0.77 | PDGFRA (0.63) | PDGFRAKDRMETAXLMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326330-B1 | Quinoline fungicides | DOW AGROSCIENCES LLC (US) | 2002-07-24 | — | — | EP | disclosed |