SCHEMBL7470574

SCHEMBL7470574

Fc1ccc(Oc2ccnc3cc(Cl)ccc23)cc1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 7/20 0.49
AXL P30530 2/20 0.48
LMNA P02545 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
HTR2A P28223 1/20 0.47
SLC6A4 P31645 1/20 0.47
KCNH2 Q12809 1/20 0.47
EGFR P00533 1/20 0.47
NR4A2 P43354 1/20 0.45
SOS2 Q07890 1/20 0.45
PDGFRA P16234 3/20 0.45
PDGFRB P09619 1/20 0.45
APP P05067 1/20 0.43
ALDH1A1 P00352 1/20 0.43
GLA P06280 1/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
ALK Q9UM73 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7456971 0.86 NR4A2 (0.51) KDRAXLLMNASMN1; SMN2HTR2A
SCHEMBL7462623 0.85 LMNA (0.54) KDRLMNASMN1; SMN2NR4A2SOS2
Hydrochloric Acid SCHEMBL27295456 0.84 NR4A2 (0.50) KDRAXLLMNASMN1; SMN2HTR2A
SCHEMBL7467633 0.82 ALK (0.50) KDRAXLLMNASMN1; SMN2EGFR
SCHEMBL7460655 0.82 LMNA (0.49) KDRAXLLMNASMN1; SMN2HTR2A
SCHEMBL7529202 0.82 NR4A2 (0.59) LMNASMN1; SMN2NR4A2SOS2APP
SCHEMBL7460710 0.81 RHEB (0.51) KDRLMNASMN1; SMN2EGFRNR4A2
SCHEMBL7465843 0.80 MAPT (0.55) KDRLMNASMN1; SMN2KCNH2NR4A2
SCHEMBL7461223 0.80 LMNA (0.52) KDRLMNASMN1; SMN2HTR2ASLC6A4
SCHEMBL7466387 0.80 NR4A2 (0.55) KDRLMNASMN1; SMN2NR4A2SOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0326330-B1 Quinoline fungicides DOW AGROSCIENCES LLC (US) 2002-07-24 EP claimed
US-5145843-A For plants DOWELANCO (US) 1992-09-08 US claimed
EP-0326330-B1 Quinoline fungicides DOW AGROSCIENCES LLC (US) 2002-07-24 EP disclosed