Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | ADA | P00813 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453033 | 0.71 | CTSG (0.44) | ADA | |
| SCHEMBL27521385 | 0.68 | ADA (0.39) | ADA | |
| SCHEMBL7451697 | 0.68 | ADA (0.40) | TSHRADA | |
| SCHEMBL7451211 | 0.65 | SMN1; SMN2 (0.45) | TSHR | |
| SCHEMBL7837953 | 0.65 | SMN1; SMN2 (0.45) | TSHR | |
| SCHEMBL10739591 | 0.64 | CYP2C19 (0.41) | — | |
| SCHEMBL8865190 | 0.64 | KEAP1 (0.47) | TSHRHDAC2HDAC8HDAC6 | |
| SCHEMBL7457016 | 0.64 | ADA (0.39) | ADA | |
| SCHEMBL9121993 | 0.62 | CYP19A1 (0.43) | — | |
| SCHEMBL10737602 | 0.62 | DHFR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001026605-A2 | IMMUNOSUPPRESSIVE COMPOSITION CONTAINING IL-2 INHIBITOR AND AN ADENOSINE DEAMINASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-19 | — | — | WO | disclosed |