Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 3/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451697 | 0.83 | ADA (0.40) | ADAFAAH | |
| SCHEMBL7857343 | 0.77 | MEN1 (0.36) | — | |
| SCHEMBL7839013 | 0.70 | ADA (0.32) | ADAFAAH | |
| SCHEMBL7453033 | 0.70 | CTSG (0.44) | ADA | |
| SCHEMBL27521385 | 0.69 | ADA (0.39) | ADA | |
| SCHEMBL8865190 | 0.66 | KEAP1 (0.47) | FAAH | |
| SCHEMBL5219663 | 0.66 | APOBEC3A (0.52) | — | |
| SCHEMBL7837953 | 0.65 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL7451211 | 0.65 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL7457145 | 0.64 | TSHR (0.35) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098885-A1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-16 | — | — | EP | disclosed |
| WO-2001026605-A2 | IMMUNOSUPPRESSIVE COMPOSITION CONTAINING IL-2 INHIBITOR AND AN ADENOSINE DEAMINASE INHIBITOR | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-19 | — | — | WO | disclosed |
| WO-2000005217-A1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-02-03 | — | — | WO | disclosed |