Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516721 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9ANPC1HPGDL3MBTL1 | |
| SCHEMBL4597773 | 0.78 | EPHX2 (0.48) | EPHX2SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL5500456 | 0.76 | MMEL1 (0.48) | EPHX2SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL7519887 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9ANPC1HPGDL3MBTL1 | |
| SCHEMBL15478278 | 0.71 | EPHX2 (0.39) | EPHX2SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL15478277 | 0.71 | EPHX2 (0.39) | EPHX2SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL15779862 | 0.71 | EPHX2 (0.39) | EPHX2SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL7873634 | 0.70 | RAB9A (0.47) | SMN1; SMN2RAB9ANPC1HPGDL3MBTL1 | |
| SCHEMBL5720860 | 0.70 | EPHX2 (0.47) | EPHX2L3MBTL1MEN1KMT2AFAAH | |
| SCHEMBL28860806 | 0.69 | EPHX2 (0.49) | EPHX2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873308-B1 | O-CARBAMOYL-PHENYLALANINOL COMPOUNDS AND THEIR PHARMACEUTICALLY USEFUL SALTS | SK CORP (KR) | 2002-01-02 | — | — | EP | disclosed |