⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6040985 | 0.93 | — | — | |
| SCHEMBL6041036 | 0.90 | LMNA (0.35) | — | |
| SCHEMBL6041009 | 0.86 | — | — | |
| SCHEMBL10931717 | 0.86 | ABCB11 (0.50) | — | |
| SCHEMBL6048121 | 0.75 | ABCB11 (0.33) | — | |
| SCHEMBL6041022 | 0.73 | FAAH (0.32) | — | |
| SCHEMBL6041027 | 0.73 | GAA (0.43) | — | |
| SCHEMBL433171 | 0.65 | — | — | |
| SCHEMBL3084917 | 0.65 | ABCB11 (0.71) | — | |
| SCHEMBL3076515 | 0.62 | LMNA (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 431 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240118285-A1 | COMPOSITIONS AND METHODS FOR T-CELL RECEPTOR IDENTIFICATION | ROOTPATH GENOMICS, INC. | 2024-04-11 | — | — | US | claimed |
| EP-4232080-A1 | COMPOSITIONS AND METHODS FOR T-CELL RECEPTOR IDENTIFICATION | Rootpath Genomics, Inc. (US) | 2023-08-30 | — | — | EP | claimed |
| WO-2022087380-A1 | COMPOSITIONS AND METHODS FOR T-CELL RECEPTOR IDENTIFICATION | ROOTPATH GENOMICS, INC. (US) | 2022-04-28 | — | — | WO | claimed |
| CN-113825771-A | Antibodies against claudin 18A2 and uses thereof | 齐鲁制药有限公司 | 2021-12-21 | — | — | CN | claimed |
| WO-2020228806-A1 | ANTIBODY AGAINST CLAUDIN 18A2 AND USE THEREOF | 齐鲁制药有限公司 | 2020-11-19 | — | — | WO | claimed |
| EP-2649998-B1 | Prolyl hydroxylase inhibitors | AERPIO THERAPEUTICS INC (US) | 2015-03-04 | — | — | EP | claimed |
| US-8883832-B2 | Compounds, compositions, and methods for preventing metastasis of cancer cells | AERPIO THERAPEUTICS INC. (US) | 2014-11-11 | — | — | US | claimed |
| US-20140249100-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR PREVENTING METASTASIS OF CANCER CELLS | AERPIO THERAPEUTICS INC. (US) | 2014-09-04 | — | — | US | claimed |
| US-8569348-B2 | Compounds, compositions, and methods for preventing metastasis of cancer cells | AERPIO THERAPEUTICS INC. (US) | 2013-10-29 | — | — | US | claimed |
| EP-2649998-A1 | Prolyl hydroxylase inhibitors | Aerpio Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | claimed |
| US-20120128625-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR PREVENTING METASTASIS OF CANCER CELLS | EyePoint, Inc. | 2012-05-24 | — | — | US | claimed |
| US-20120121692-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING CDK INHIBITORS AND METHODS FOR TREATING CANCER | SHANDONG UNIVERSITY (CN) | 2012-05-17 | — | — | US | claimed |
| EP-2451279-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR PREVENTING METASTASIS OF CANCER CELLS | Akebia Therapeutics Inc. (US) | 2012-05-16 | — | — | EP | claimed |
| EP-2429292-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING CDK INHIBITORS AND METHODS FOR THE TREATMENT OF CANCER | Georgia State University Research Foundation, Inc. (US) | 2012-03-21 | — | — | EP | claimed |
| US-20110111058-A1 | METHODS FOR INCREASING THE STABILIZATION OF HYPOXIA INDUCIBLE FACTOR-1 ALPHA | AERPIO THERAPEUTICS LLC | 2011-05-12 | — | — | US | claimed |
| WO-2011005330-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR PREVENTING METASTASIS OF CANCER CELLS | AKEBIA THERAPEUTICS INC. (US) | 2011-01-13 | — | — | WO | claimed |
| WO-2010129858-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING CDK INHIBITORS AND METHODS FOR THE TREATMENT OF CANCER | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-11-11 | — | — | WO | claimed |
| US-12043664-B2 | Methods for treating vascular leak syndrome and cancer | EyePoint Pharmaceuticals, Inc. (US) | 2024-07-23 | — | — | US | disclosed |
| WO-2001000196-A2 | MIRTAZAPINE FOR WEIGHT GAIN IN WASTING DISEASES | UNIVERSITY OF SOUTH FLORIDA (US) | 2001-01-04 | — | — | WO | disclosed |
| WO-2000010391-A1 | THE USE OF ADENOSINE A3 RECEPTOR ANTAGONISTS TO INHIBIT TUMOR GROWTH | MEDCO RESEARCH, INC. (US) | 2000-03-02 | — | — | WO | disclosed |