⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10931717 | 1.00 | ABCB11 (0.50) | — | |
| SCHEMBL745787 | 0.86 | — | — | |
| SCHEMBL6040985 | 0.86 | — | — | |
| SCHEMBL6041036 | 0.83 | LMNA (0.35) | — | |
| SCHEMBL6048121 | 0.81 | ABCB11 (0.33) | — | |
| SCHEMBL6041022 | 0.78 | FAAH (0.32) | — | |
| SCHEMBL433171 | 0.77 | — | — | |
| Thiotepa SCHEMBL4760 | 0.67 | ABCB11 (1.00) | — | |
| SCHEMBL10931251 | 0.61 | DPP4 (0.33) | — | |
| SCHEMBL628124 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3953394-A1 | PIP4KS SUPPRESS INSULIN SIGNALING AND ENHANCE IMMUNE FUNCTION THROUGH A CATALYTIC-INDEPENDENT MECHANISM | Cornell University (US) | 2022-02-16 | — | — | EP | disclosed |
| CN-107847610-B | PIV 5-based amplification virus-like particles | 塞维卡有限责任公司 | 2022-02-01 | — | — | CN | disclosed |
| WO-2020210686-A1 | PIP4Ks SUPPRESS INSULIN SIGNALING AND ENHANCE IMMUNE FUNCTION THROUGH A CATALYTIC-INDEPENDENT MECHANISM | CORNELL UNIVERSITY (US) | 2020-10-15 | — | — | WO | disclosed |
| US-20200071399-A1 | MULTIPARTITE SIGNALING PROTEINS AND USES THEREOF | BLUEBIRD BIO, INC. (US) | 2020-03-05 | — | — | US | disclosed |
| EP-3331558-A1 | COMBINATION THERAPIES TARGETING MITOCHONDRIAL BIOGENESIS FOR CANCER THERAPY | The Wistar Institute Of Anatomy And Biology (US) | 2018-06-13 | — | — | EP | disclosed |
| EP-3212668-A2 | ANTI-CS1 ANTIBODIES AND ANTIBODY DRUG CONJUGATES | AbbVie Biotherapeutics Inc. (US) | 2017-09-06 | — | — | EP | disclosed |
| WO-2017024207-A1 | COMBINATION THERAPIES TARGETING MITOCHONDRIAL BIOGENESIS FOR CANCER THERAPY | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2017-02-09 | — | — | WO | disclosed |
| WO-2016070089-A2 | ANTI-CS1 ANTIBODIES AND ANTIBODY DRUG CONJUGATES | ABBVIE BIOTHERAPEUTICS INC. (US) | 2016-05-06 | — | — | WO | disclosed |
| EP-1632253-A1 | Material for odour control | BKI Holding Corporation (US) | 2006-03-08 | — | — | EP | disclosed |
| WO-2006017441-A1 | MATERIAL FOR ODOR CONTROL | BKI HOLDING CORPORATION (US) | 2006-02-16 | — | — | WO | disclosed |
| US-20060029567-A1 | Material for odor control | BKI HOLDING CORPORATION (US) | 2006-02-09 | — | — | US | disclosed |
| EP-0119487-B1 | NOVEL N-ALIPHATIC AND N,N-ALIPHATIC PHOSPHORIC TRIAMIDE UREASE INHIBITORS AND UREASE INHIBITED UREA BASED FERTILIZER COMPOSITIONS | ALLIED CORPORATION (US) | 1986-07-16 | — | — | EP | disclosed |
| US-4530714-A | Capable of forming urea under use conditions | ALLIED CORPORATION (US) | 1985-07-23 | — | — | US | disclosed |
| EP-0119487-A1 | Novel N-aliphatic and N,N-aliphatic phosphoric triamide urease inhibitors and urease inhibited urea based fertilizer compositions | ALLIED CORPORATION (US) | 1984-09-26 | — | — | EP | disclosed |