Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 18/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3178699 | 0.86 | GAA (0.48) | PTGDR2 | |
| SCHEMBL6895646 | 0.81 | PTGS2 (0.58) | PTGDR2 | |
| SCHEMBL6598899 | 0.80 | PTGDR2 (0.43) | PTGDR2 | |
| Bromide SCHEMBL6897206 | 0.77 | HTT (0.55) | PTGDR2 | |
| SCHEMBL3308684 | 0.76 | ALDH1A1 (0.55) | — | |
| SCHEMBL3185077 | 0.71 | PTGDR2 (0.43) | PTGDR2 | |
| SCHEMBL8922687 | 0.71 | PTGDR2 (0.46) | PTGDR2 | |
| SCHEMBL7462975 | 0.70 | TRPM8 (0.47) | — | |
| SCHEMBL7467556 | 0.70 | HTR2A (0.36) | PTGDR2 | |
| SCHEMBL27428321 | 0.69 | PTGS2 (0.43) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0940401-B1 | 2-CARBONYLTHIAZOLE DERIVATIVES AND USE OF THE SAME | TAISHO PHARMACEUTICAL CO LTD (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-6166033-A | 2-carbonylthiazole derivatives and use of the same | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0940401-A1 | 2-CARBONYLTHIAZOLE DERIVATIVES AND USE OF THE SAME | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1999-09-08 | — | — | EP | disclosed |